Friday, February 25, 2011

Relationship between Food and Fertility

Hi,
today I went on to have an aggressive discussion with a dear friend of mine on whether there exists any relation between the diet of a female and her fertility. I happened to remember this from various discussion with people I believe had some real knowledge. But, my friend insisted that there is no written proof on any such connection. I hope the below material can give some hint that indeed there is some link between a female's food habits and her fertilty..

Nonetheless, there might be something which might be of general interest to many females out there. Therefore, I thought I must post it on my blog.. it may help some body. But of course, read the caveat below ..


Two most important lines that I can quote are

"that during starvation, adult nematode worms can put reproduction on hold – destroying any existing sex cells and regenerating a new crop of healthy eggs from a few remaining stem cells once conditions improve."

"Anorexia or starvation causes difficulties in conceiving and carrying a baby to term."


HOWEVER, NONE OF THE BELOW INFORMATION IS MEANT TO BE CONCLUSIVE THEREFORE DO NOT DRAW ANY CONCLUSIONS OR CHANGE YOUR DIETARY HABIT UNLESS YOU UNDERSTAND THE TEXT PERFECTLY WELL OR AT LEAST CONSULT YOUR DOCTOR FIRST.



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For extensive details/solutions/causes on Female infertility do read at
http://www.digitalnaturopath.com/cond/C382617.html

 
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Fasting and Female Fertility
from http://fasting.ygoy.com/2009/12/09/fasting-and-female-fertility/
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Can fasting be a remedy for older women to become pregnant is the topic of latest studies. It has not yet established yet but the research is carried out in mice. This article gives some facets of the topic.


How fasting is related to fertility:
In ancient times women used to fast to conceive. Several types of fasting were recommended for certain cases of infertility and it was considered that children conceived by taking up penances like fasting are more inclined to spirituality. Fasting is also counted as a home remedy for women who are unable to bear children. A short tern fast of two or three days is recommended at regular intervals by women who have problems in conceiving.


Research Studies in Mice:
The first study on this topic was done by Jonathan Tilly and his colleagues at Harvard Medical School, Boston. Adult female mice were considered and the calorie intake of the mice were reduced by 40 percent. This was observed for 12 months as the reproductive year of the mouse was increased to one year. The results were compared to the mice that were fed normally or fed more, as they like.


The results showed that the eggs of the mice that fast had fewer chromosomal abnormalities that those mice who did not fast. These abnormalities were studied because chromosomal abnormalities increase the risk of birth defects and miscarriage in both mice and humans.


The results also showed that the mice that fasted also produced more eggs compared to mice who were fed. The findings also relate that fasting artificially stimulated the formation of eggs. The eggs found were more susceptible to develop into embryos after fertilization. In other the results showed that the quality of the eggs of mice that fasted were good compared to those mice that did not fast.


The above content is only the information about the research but not the report or authentication of the results of the experiment.


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Fasting could extend female fertility

Journal references:
Tilly: Aging Cell, DOI: 10.1111/j.1474-9726.2008.00409.x;
Van Gilst: Science, DOI: 10.1126/science.1178343
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Could fasting allow older women to have children? That's the implication of two new studies which suggest that restricting food may offset some of the loss of egg quality and quantity that comes with ageing. The findings may even enable new eggs to be created from scratch.

It's not yet clear whether the findings extend to humans, but a better understanding of the mechanisms involved might eventually make it easier for older women to bear children.

In the first study, Jonathan Tilly and his colleagues at Harvard Medical School reduced the calorie intake of adult female mice by 40 per cent and found that significantly fewer of their eggs had abnormal chromosomes once the mice reached the age of 12 months – advanced reproductive years in mouse terms – compared with mice that were allowed to eat as much as they liked.

Such abnormalities in eggs are known to increase the risk of miscarriage and birth defects in older mothers, both mouse and human.

Eggs up

Calorie-restricted mice also produced more eggs than normal mice when their ovaries were artificially stimulated, and their eggs were more likely to develop into embryos upon fertilisation.

"Our data show that adult-onset caloric restriction prevents the age-related decline in oocyte [egg precursor cell] quality and quantity," says Tilly, who is presenting his results at a meeting organised by the SENS (Strategies for Engineered Negligible Senescence) Foundation in Cambridge, UK, next week.
Last year, Tilly's team announced that restricting the calorie intake of adult mice extended the mice's reproductive lifespan and increased the chances of their offspring surviving after birth.

"It continues to show how little we know about the mechanisms that are involved in regulating [egg] growth, development and quality," says Evelyn Telfer of the University of Edinburgh, UK, who also researches egg development. "Manipulating nutrition is clearly modifying underlying signalling pathways."

One possibility is that restricting food intake affects the interactions between developing eggs and their support cells, says Telfer. Or it could alter the activity of germ-line stem cells, which some think could replenish depleted ovaries under the right conditions.

Starving worms

That's where the second study may provide insights. Marc Van Gilst and Giana Angelo at the Fred Hutchinson Cancer Research Centre in Seattle have shown that during starvation, adult nematode worms can put reproduction on hold – destroying any existing sex cells and regenerating a new crop of healthy eggs from a few remaining stem cells once conditions improve.

Worms that undergo this process also seem to extend their lifespan up to threefold.

Van Gilst suspects that a signalling protein called NHR-49, already known to be involved in the metabolic response to fasting, is involved: "In worms that contained an inactive NHR-49 gene, reproductive recovery and fertility after starvation were severely impaired," says Van Gilst.

From worm to human

He thinks a similar process might exist in humans. This is yet to be tested, however, and the trigger needed to activate such a signalling pathway has not been identified. "It might have evolved to help our ancestors preserve fertility during times of famine," he says.
One protein that might do the job in humans is called PPAR gamma, which is analogous to NHR-49 and appears to control the rate of ovulation.
It is also unclear how much caloric restriction would be needed to turn on such a system in humans – assuming we have it at all. But if the underlying signalling molecules could be identified, and ways found to manipulate them, it could help treat a variety of fertility problems and even extend female reproductive lifespan, says Telfer.
"Fundamentally, if you can understand how eggs initiate into the growing population and you can slow it down, then you would be extending female fertility."

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Shrinking Fibroids & Increasing Fertility Naturally
WATER FASTING
from http://shrinkingfibroids.blogspot.com/2009/02/water-fasting-estrogen-dominance-and.html
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Anonymous said...


Hi,



Just want to share this info that Water-only fasting really work. The detox was still working even after I broke the fast by eating fresh fruits & vegetables. I could no longer feel any solid mass on my abdomen.


I tried water-only fasting for 2 weeks this past August. After I broke the fast, I was still eating mostly fresh fruits & vegetables. In August, I went to get sonogram, the fibroid shrank by more than 30% after water-only fasting. Then in Sept and part of Oct, the detox was still ongoing because I was eating raw garlic mixed with fresh squeeze juices. I also sprinkle curry spice on all my food. Garlic & curry support the liver in the Phase II detox.


In Sept & early Oct, I had stabbing pain in the area where I had the fibroid. At first, I was scared that it was growing bigger. But it was simply detox reactions. The raw garlic I eat everyday is supposed to cut off the blood supply of tumor. Therefore, the fibroid was losing blood supply.


One week after the stabbing pain stopped, I couldn't feel any solid mass, I only felt some soreness in my right abdomen. It's been about 2 weeks now, even the soreness feeling is gone. And of course, I couldn't feel any solid mass anymore.


Besides getting rid of the large fibroid via water-only fasting, my blood pressure is lowered. It was originally around 120/70-ish. After the water-only fasting & continuing with healthy food, my blood pressure drop to 100/60-ish range. It's a 20 point reduction in blood pressure.


Water-only fasting is truly amazing. Of course, you should check out library books on Fasting before starting it. I used this book written by Bruce Fife that I borrowed from the library. It's a good book, I highly recommend it to people to treat many ailments.


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Dairy foods and ovulation
(From http://www.ivf1.com/dairy-foods-ovulation-infertility/)
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Lactose is the main carbohydrate in milk and other dairy foods. In the intestine, lactose is broken down into two sugars, glucose and galactose, which are further broken down and used by the body.


The ability to breakdown these sugars is an important factor in normal ovarian development. for example, women with a disease that prevents the breakdown of galactose often develop premature ovarian failure.



Some researchers have suggested that high intake of milk and dairy products may increase the risk of infertility due to ovulatory dysfunction in otherwise healthy women. However, study results are not consistent. In fact, there are reasons to believe that dairy foods may be beneficial to ovarian function, and that not all dairy foods have the same relation to fertility. For example, dairy food intake has been associated with a lower risk of developing insulin resistance, which is a cause for not ovulating.


In order to try and better answer these question, researchers conducted a study to determine whether the intakes of low-fat dairy foods, high-fat dairy foods, lactose and other nutrients concentrated in dairy foods were associated with infertility due to ovulation problems in a large group of otherwise healthy women.


The Nurses Health Study II started in 1989 when more than 116 000 female registered nurses aged 24–42 completed and returned a mailed baseline questionnaire. The nurses have been followed every 2 years since then with additional questionnaires. Only married women, with available dietary information and without a history of infertility, were analyzed for this study.


In total, 18 555 women were found without a history of infertility who tried to become pregnant or became pregnant during the 8-year period that the study was conducted.



Dietary assessment
The nurses were asked about more than 130 food items and 11 individual dairy foods. Participants were asked to report how often, on average, they consumed each of the foods and beverages during the previous year. This questionnaire had previously been validated in other studies as an accurate way to estimate a persons intake of dairy foods and nutrients concentrated in them.


The women differed in several important areas. Women who consumed more low-fat dairy foods were less likely to smoke or drink high amounts of coffee and exercised more. Women who consumed more high-fat dairy foods were more likely to drink alcohol, more likely to have previously been pregnant and were less likely to exercise. In addition, women consuming more dairy foods, regardless of fat content, were also more likely to use multivitamins and less likely to use oral contraceptives.


Infertility assessment
During the eight year study, 26 971 pregnancies or pregnancy attempts were reported by among 18 555 women. 438 women reported developing infertility, underwent medical evaluation and were diagnosed with an ovulation problem.
Results of this study
Intake of total dairy foods was not associated with risk of ovulatory problems.


However, women who had a high intake of low fat dairy food were more likely to experience ovulation problems. An increase in low-fat dairy foods of 1 serving per day was associated with an 11% greater risk of an ovulation problem resulting in infertility.


Women who had a high intake of high fat dairy foods were less likely to have ovulation problems.


Interestingly, the researchers were not able to demonstrate a correlation between intake of lactose and the development of ovulation problems.


The results for specific dairy foods generally followed the same way. Among the low-fat dairy foods, adding one serving per day of yogurt or sherbet/frozen yogurt was associated with a greater risk of anovulatory infertility. Women who drank one or more servings per week of skim/low-fat milk also had a significantly higher risk compared with women who drank less than one serving per week.


The researchers also tried to identify the type of woman that might be most affected by low fat dairy foods. The strongest associations were for women who were older than 32 years of age, had a lower body mass (less than 25 kg/m2) and who had been pregnant previously.
Results of previous studies
Only two previous studies have examined whether intake of milk or dairy foods could affect fertility in women. In 1994, one study found that the higher amount of milk women drank, the greater the chances for having fertility. However, a 2003 study found that women who drank three or more glasses of milk daily had a 70% lower risk of infertility when compared with women who did not drink milk at all.



Alternative conclusions
It is possible that the diets these nurses followed may have changed as a result of their having problems getting pregnant rather than the other way around. It is also possible that other ingredients found in low or high fat milk may be affecting the chances for ovulation problems The study authors state that they cannot exclude the possibility that lactose, calcium, phosphorus or vitamin D could have had some effect on ovulation in these nurses.



Don't draw too many conclusions
It is also important to point out what the study did not demonstrate. This study was not designed to detect if a specific length of time was necessary to develop problems with ovulation. It also did not show whether switching to high fat dairy consumption would reverse the problems in ovulation that seemed to have occurred in women who had higher intake of low fat dairy foods.


The study controlled for the total amount of calories consumed. It would not be recommended that women increase their calorie intake as this could result in weight gain, which is another cause for ovulation problems.


High fat diets are known to have other significant health issues such as weight gain and heart disease. Women should take these other factors into account before making changes to their diet.

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